NHL: Leafs vs. Sabres Picks and Odds, October 24, 2025

Another divisional matchup for tonight and we have you covered. The Toronto Maple Leafs will take on the Buffalo Sabres. This is the first time of four games they’ll play this year.

Toronto is 3-3-1 to start the season and 4th in the Atlantic. They come into this game on a two-game losing streak they’ll be looking to snap. The Leafs are 0-1-0 on the road, so they’ll also be looking for that first win.

Their last game was against the Devils on Tuesday night and they lost 5-2. They got on the board first with a goal in the first period but then let up three goals in the first five minutes of the second period. Jack Hughes iced the game for the Devils with a hat-trick.

Goalie Anthony Stolarz saved 30 of the 34 shots he faced. He is 2-3-1 on the year with a 3.01 GAA and a .894 save percentage. Stolarz is expected in net tonight again.

Check out the odds for this matchup and other NHL games at the best online sportsbooks.

Buffalo looks to grab fourth win at home after win Wednesday

Leafs center Auston Matthews stands in front of the Buffalo net looking for the puck.

The Sabres are 3-4-1 to start and are 5th in the division. They come into this game off a win over the Red Wings on Wednesday night. Buffalo has played better at home than on the road with a 3-2-0 record.

They were able to put four goals in on Wednesday, which was nice to see out of them. Buffalo is only 21st in goals scored, but 8th in shots on goal per game. The Sabres may shoot a lot, but their shooting percentage is 25th in the league.

Defense is not looking good for the Sabres. They rank 16th in goals allowed and 31st in the shots on goal allowed per game. Buffalo does have a nasty penalty kill that ranks 2nd in the league and they’re averaging 5 penalties per game.

Goalie Alex Lyon is expected in net. Lyon is 2-4-0 this season with a 2.54 GAA and a .924 save percentage. Let’s check out the odds and get into the Leafs vs. Sabres picks.

Toronto Maple Leafs vs. Buffalo Sabres Betting Odds and Game Information

Leafs vs. Sabres Betting Odds – October 24

Puck Line

Toronto Maple Leafs -1.5 (+194)
Buffalo Sabres +1.5 (-245)

Moneyline

Toronto Maple Leafs -126
Buffalo Sabres +105

Totals

Over 6.5 (+108)
Under 6.5 (-132)

Odds courtesy of BetOnline – Get 50% up to $1000 on your first deposit

Leafs vs. Sabres Game Information

Venue: KeyBank Center, Buffalo, NY
Date: Friday, October 24, 2025
Puck Drop: 7 p.m. EST
TV: ESPN+

Toronto Maple Leafs vs. Buffalo Sabres Picks and Prediction

Maple Leafs center Auston Matthews celebrates with teammates after scoring a goal.

Leafs vs. Sabres Picks and Predictions: Toronto Maple Leafs Moneyline (-126) Get 50% up to $1000 Deposit on BetOnline for this pick

Give me the offensive powerhouse that is the Toronto Maple Leafs. Their offense is so powerful, and I don’t think the Sabres will have any answer for them. The Leafs need to step up on the power play and could be even more dangerous.

Buffalo really hasn’t shown much to prove to me they can win this game. This is also a great bounce back spot for the Leafs after losing two games. Stolarz hasn’t been terrible this season and if they can give him some support, they can win this game.

I like William Nylander to keep tearing it up and dishing the puck. He has 11 assists so far and 2 in each of his last 4 straight games. Give me his assist and 2 or more assists as well for plus money.

The other play I like is Rasmus Dahlin for 3 or more shots on goal. He has hit in 4 of his last 5 games and is coming off a miss which we like. Dahlin is their top defenseman and will quarterback their power plays from the top of the key, firing at the net.