We’ve got a divisional battle in the AFC South. The Titans will travel to Indianapolis to take on Indiana Jones and the Colts.
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Game Information
Matchup Information
- Location: Lucas Oil Stadium; Indianapolis, Indiana
- Date: Sunday, October 26th, 2025
- Kickoff: 4:25 PM EST
Quarterback Matchup
- Tennessee Titans: Cam Ward (2024 – n/a)
- Indianapolis Colts: Daniel Jones (2-8; 2024 – 207.0 YPG | 8 TD | 7 INT)
Betting Odds
Odds via BetOnline, an industry leader in the sports betting world.
Analysis & Breakdown
Indiana Jones
Daniel Jones is playing like an MVP and you can’t really debate it. In his first year with the Colts, Indiana Jones is completing 71% of his passes, averaging 255.7 yards per game with 10 passing touchdowns, four rushing touchdowns and three interceptions. Jones is having a career year and it’s why the Colts are 6-1 with the best record in the NFL.
Indianapolis ranks 1st in points scored, 1st in first downs, 1st in yards per play, 5th in pass yards and 7th in rush yards. The team’s scoring on 68% of their redzone drives (8th) and convert on 47% of their third downs (4th). The entire offense is firing and the defense has done a great job of keeping up.
The Colts rank 8th in points allowed, 6th in rush yards allowed, 4th in turnovers generated and 8th in sacks. The team’s had a tough time against opposing pass attacks but some of that stems from the fact their opponents have been forced to pass the ball at a higher frequency.
Bad, just really bad
The Titans are just kinda bad. The offense ranks dead last in points scored, first downs, third down conversion rate, yards per play and have done a terrible job of keeping Cam Ward protected. The offense ranks 31st in pass yards this year, 31st in rush yards and have 11 turnovers on the year.
This week the Titans 32nd ranked offense will go head to head with the Colts 1st ranked offense. This is the definition of David vs. Goliath.
The Titans come into this game as a 15-point underdog on the road, with the total set at 48. Oddsmakers are telling us we’re going to see points in this game and with how the Titans have been defensively; majority of those points will come from Indianapolis. Tennessee ranks 28th in points allowed, 29th in rush yards allowed, 23rd in yards per play and have not generated pressure against opposing QBs.
Sunday’s Best Bet
Alec Pierce o37.5 Receiving Yards (-110) | BetOnline
Someone we haven’t bet all year, but this feels like the perfect week to do so. Alec Pierce is a 6’3 wideout out of Cincinnati that the Colts drafted in the 2nd round of the 2022 NFL Draft. He’s now 25 years old and he’s gotten better every single year, despite terrible quarterback play. Prior to Danny Dimes, he spent time with Matt Ryan under center, Joe Flacco and of course Anthony Richardson.
Last year Pierce averaged 51.5 receiving yards per game and finished with seven touchdowns on the year. He lead the team in touchdowns last year and this year he’s become the Colts’ bonafide WR2. Pierce has played in five of the Colts’ seven games, cleared this line in four of the five. He also leads the team in targets of 20+ yards, despite playing two fewer games.
Tennessee ranks bottom-12 in EPA per play allowed, success rate allowed, QB pressure rate and explosive pass plays allowed. Pierce ranks 3rd in the NFL in yards per reception this year, averaging 19.8 yards per catch. His average depth of target is 21.1 yards and the Titans have allowed a pass play of 29+ yards in six straight games.
This week the Titans will be without L’Jarius Snead and it’ll be Jalyn Armour-Davis taking his place. Armour-Davis ranks 91st in coverage grade this year and is allowing a 75% catch rate,15.9 yards per catch and a passer rating of 114.2 when targeted. Whoever suits up for the Titans, I’m all in on Pierce this week.
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