Titans vs Colts Week 5 Prediction, Odds & Picks: Henrymania Runs Wild

Titans vs Colts prediction, odds & picks

The NFL Week 5 lineup has its fair share of rivalry games, including Sunday’s AFC South collision between the Tennessee Titans and Indianapolis Colts at 1 p.m. ET.

The Titans head back to the road looking to build more momentum after notching a 27-3 win over the Cincinnati Bengals. Meanwhile, the Colts couldn’t pull off the comeback win in Week 4, losing 29-23 to the LA Rams in overtime.

Can Tennessee prove that its latest victory wasn’t a fluke? Or will Indianapolis find a way to stand tall?

Read on for Betting News’ full Titans vs. Colts betting preview, including the latest game odds to my best bets and predictions for the showdown.

Titans vs Colts — NFL Week 5

TEN vs IND Game Information

  • Matchup: Tennessee Titans (2-2, 0-2 Away) vs. Indianapolis Colts (2-2, 0-2 Home)
  • Venue & Location: Lucas Oil Stadium (Indianapolis, IN)
  • Date: Sunday, Oct. 8, 2023
  • Game Time: 1 p.m. Eastern Time
  • Titans vs. Colts Week 5 TV Channel: CBS

Titans vs Colts Odds

NFL game odds courtesy of Bovada as of Saturday, Oct. 7 at 7:24 p.m. ET. Odds from other sportsbooks may also be mentioned in this article.

Spread

  • Tennessee Titans -2.5 (-110)
  • Indianapolis Colts +2.5 (-110)

Over/Under

  • Over 43 Points (-115)
  • Under 43 Points (-105)

Moneyline

  • Tennessee Titans -135
  • Indianapolis Colts +115
4.5/5 Review Rating
Bonus & Benefits
50% Up to $750
See our review »
Best Prop Bets Selection
Boosted Odds on Parlays
One of the Oldest and Trusted Sites

Related NFL Betting Stories

Titans vs Colts Betting Trends

  • Tennessee is 5-0 straight up in its last five games against Indianapolis.
  • Indianapolis is 16-4 straight up in its last 20 Week 5 matchups.
  • Tennessee is 4-1 ATS In its last five road games against Indianapolis.
  • Indianapolis is 0-5 ATS in its last five home games.
  • The total has hit the under in five of Tennessee’s last six AFC South matchups.
  • The total has hit the Over in five of Indianapolis’ last seven AFC matchups.

Titans vs Colts Week 5 Preview

The Colts haven’t had much luck when it comes to this AFC South rivalry as of late. They’ve dropped five consecutive games to the Titans, losing by an average margin of 9.4 points.

If Indianapolis is to win, the first thing it must do is slow down Tennessee’s run game. After all, the visitor’s offense runs through RB Derrick Henry.

Unfortunately, the Colts haven’t done that great of a job defending on the ground. Inconsistent play from the defensive line has seen them allow 126.8 rushing yards per game (10th-most) as well as four rushing TDs to running backs — tied for the sixth-most in the NFL.

It’s also worth noting that Henry consistently terrorizes the Colts. The three-time Pro-Bowler has racked up 853 rushing yards and five TDs in his last seven encounters with Indianapolis, finishing with no fewer than 103 yards in all but one of those games.

Titans vs Colts Prediction, Odds & picks Week 5
Titans RB Derrick Henry has 957 total yards from scrimmage and five TDs in his last seven games against the Colts.

The Titans also have momentum stemming from a strong defensive performance in last week’s win over the Bengals.

Tennessee held Cincinnati to just 211 total yards, as well as an average of 4.1 yards per play. The Bengals also converted on just 2-of-9 third downs (22.2%) and failed to score on their only trip to the red zone.

Given that the Bengals have more offensive talent than the Colts, it wouldn’t be shocking if the home team struggles to get the ball rolling early on.

Even as solid as Indianapolis QB Anthony Richardson has been, he still has a lot to learn — highlighted by last week’s 44.0% completion rate. He’s also been sacked six times in three starts and now faces the Titans, who are up to 13 sacks this season (T-7th).

If Richardson can’t consistently make his passes early on, the Colts could be playing from behind again this weekend.

4.5/5 Review Rating
Bonus & Benefits
50% Up to $750
See our review »
Best Prop Bets Selection
Boosted Odds on Parlays
One of the Oldest and Trusted Sites

Titans vs Colts Prediction — Week 5

In a game that could go either way, I see the Titans standing tall at the final whistle. Not only are the Colts struggling to beat their divisional rival, but the fact that they were down 20-0 at halftime last week raises some serious concerns.

It’ll be a fun back-and-forth affair, but look for the Titans’ run game to give them the edge.

Prediction: Titans 20, Colts 17

Bet: Under 43 Points (-105 on Bovada)

Titans vs Colts Player Prop — Week 5

When it comes to a Titans vs. Colts player prop, it’s an absolute no-brainer to take Derrick Henry to finish with over 75.5 rushing yards.

For starters, the former Alabama product has hit the Over on this prop twice in his last three games, which includes last week’s 122-yard performance. Secondly, he’s finished with 76-plus rushing yards in 10 of his last 12 games against the Colts, averaging 107.0 yards during that span.

With Indy’s run defense looking suspect at best, hitting the Over won’t be an issue for Henry.

Bet: Derrick Henry Over 75.5 Rushing Yards (-115 on Bovada)


Tennessee vs Indianapolis Week 5 FAQ

When is Titans vs Colts?

  • The Titans and Colts will collide on Sunday, Oct. 8, 2023.

Where is Titans vs Colts?

  • The Titans and Colts will play each other at Lucas Oil Stadium in Indianapolis, Indiana.

What time does Titans vs Colts start?

  • Kickoff for the upcoming TEN vs. IND matchup is slated for 1 p.m. ET.

How can I watch Titans vs Colts?

  • Tennessee and Indianapolis fans can tune in to CBS for Sunday’s matchup.

How can I bet on Titans vs Colts?

1
Lucky Rebel Sportsbook logo 4.9/5 Review Rating
Bonus & Benefits
Up to $1,250 + 50 Free Slots Spins
See our review »
$1,250 Welcome Bonus
Bet Live on Your Favorite Sports
Earn More with Rebel Rewards!
2
4.8/5 Review Rating
Bonus & Benefits
55% Welcome Bonus w/ code BNBOL55
See our review »
Up to $250 in Free Bets + 100 Spins
$10 Cash Bonus w/ Code BNEWS
Fastest Payouts
3
4.7/5 Review Rating
Bonus & Benefits
100% up to $1000 Sign-Up Bonus
See our review »
Bonus Code: WELCOME1000
Monthly Cash Prizes
Vast Lines and Games Selection
4
4.6/5 Review Rating
Bonus & Benefits
55% Welcome Bonus w/ code BNSB55
See our review »
$250 in Free Bets with First Deposit
Same Game Parlays
Frequent Odds Boosters
5
4.5/5 Review Rating
Bonus & Benefits
50% Up to $750
See our review »
Best Prop Bets Selection
Boosted Odds on Parlays
One of the Oldest and Trusted Sites
6
4.4/5 Review Rating
Bonus & Benefits
125% Welcome Bonus
See our review »
Anonymous Crypto Betting
125% Welcome Bonus
Great Live Betting Selection
7
4.3/5 Review Rating
Bonus & Benefits
125% Deposit Bonus
See our review »
Fast & Easy Payouts
Best Deposit & Free Play Bonuses
Largest Selection of Sports & Games
8
4.2/5 Review Rating
Bonus & Benefits
125% Up to $3,125
See our review »
Best All Around Sportsbook
Most Competitive Odds
Sports, Casino, Poker & Racebook
9
4.1/5 Review Rating
Bonus & Benefits
100% Up to $1,000
See our review »
Free Contests for Real Money
Bet on Esports
Sportsbook, Casino & Racebook
10
4.0/5 Review Rating
Bonus & Benefits
Up to $1,000 Sign-Up Bonus
See our review »
100% of Your First Deposit
$10 Casino Chip
Limited Time Only