NFL Preseason Picks and Predictions: August 23, 2025

Spencer Rattles looks to guide his team to their second win of the season.

Today marks the last day of the NFL Preseason. All that means is we are one step closer to the regular season, meaning football will be on our screens for several straight months. Rejoice, ladies and gentlemen, we have made it to the fall. Of course, the talk around town is the fact that college football kicks off with Week 0 today, however we still had to dive into this NFL Preseason slate and find our favorite picks for the day. Let’s get to it!

Check out the latest odds at the best online sportsbooks. Plus, take some time to check out our NFL Divisional Previews below.

Denver Broncos vs. New Orleans Saints NFL Picks

Will Tyler Shough start Week 1 for the Saints?

Best Bet: DEN/NO Under 40.5 (-105) BetOnline

Here we go again betting another preseason under. Look, I am very low on the Saints overall this season. Sure, Tyler Shough and Spencer Rattler are in a very tight starting QB race, and both will bring their A-game today. But will it be enough?

Personally, I have little faith in those guys moving the ball, especially against a defense like Denver’s. Now, the Broncos’ starters will probably only see the field for a series or two, but the depth on that side of the ball will certainly show.

Even with New Orleans being at home and likely going all out offensively for this matchup, I don’t think we see both teams put up 20 points, likely keeping this one under.

Seattel Seahawks vs. Green Bay Packers NFL Picks

Jalen Milroe will likely play the entire game tonight in Green Bay

Best Bet: Seattle Seahawks +3 (-108) BetOnline

I like the Seahawks to keep this within a field goal on the road, let me explain why.

Jalen Milroe will probably play the entire game. Yes, the entire game. While that means we won’t see Sam Darnold, it does mean that: 1) The Seahawks have faith in Milroe and want to see what he can do for a full 60 minutes, and 2) Seattle will let Milroe ball out and try to win this game. They see him as a potential QB2 behind Darnold, so they’ll want to make sure he is totally up to speed if his number gets called in the regular season.

As for the Packers, Jordan Love likely remains sitting, so Malik Willis will lead the offense. He has shown signs of life both last year and in the preseason so far, but I think the Seahawks have a little bit more to play for in this one.

Look for Milroe to show out as if he was back at Alabama.

Jacksonville Jaguars vs. Miami Dolphins NFL Picks

Tua will play at least a drive or two tonight for Miami

Best Bet: Dolphins 1H -4 (-118) BetOnline

Let me be honest, I missed the best number. Miami opened up at just 3.5 point favorites, but after announcing they will play starters and the Jaguars won’t, this has ballooned up to a six point spread. I’ll take a stab at the first half, thinking Miami can put some points on the board early.

For starters, Liam Coen has said Jacksonville will sit all of their starters, both offensive and defensive. The Jaguars’ offense is already painful to watch with Trevor Lawrence, and without him, it will be even more difficult to score.

Now, I don’t have tons of faith in the Dolphin’s offense this season, but I do think Tua can put up some points against backups. Whenever he gets pulled, Quinn Ewers and Zach Wilson will also be more than capable of moving the ball against a second string defense, as we saw last week in Miami’s comeback in the fourth quarter.

I think this time around, the Dolphins jump out to at least a touchdown lead by the break, cashing our spread.

Las Vegas Raiders vs. Arizona Cardinals NFL Picks

Aiden O’Connell and Cam Miller lead the Raiders in their preseason finale

Best Bet: LV/AZ Under 37.5 (-104) BetOnline

It ain’t rocket science. Neither team will play their best players, so that makes me lean towards the under.

Arizona showed signs of life against the Kansas City Chiefs in the opening week, but looked horrendous without Kyler Murray or any of their top weapons against the Denver Broncos last week. Sure, Jacoby Brissett is a competent quarterback, but he played just two drives last week. We will probably see even less of him this week, giving Clayton Tune the full keys to the offense.

As for the Raiders, Aiden O’Connell has struggled with three preseason picks in just two games, and rookie Cam Miller is still getting used to the speed of the NFL. Ultimately, I see both offenses struggling to move the ball, as they have all preseason, resulting in a low scoring, sloppy under for us.

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NFL Preseason Picks and Predictions (8/23): Teams Wrap Up Competition Before Real Deal