2025 Heisman Trophy: Odds Update and Insights | December 1, 2025

Indiana quarterback Fernando Mendoza (#15) celebrates with teammates - #2 Indiana vs. Penn State Prediction & Best Bets (11/8/2025)
The college football season has reached its final turn, and the Heisman conversation has never felt more intense. Championship week is here, and every matchup carries serious weight for the award that defines a season. Two quarterbacks have separated from the pack, and their final showcase will shape how voters see the entire body of work. If you follow the market, this is the moment when every number matters and every angle deserves attention. Scroll down, lock in, and take a deeper look at where the value sits as the Heisman race hits its final stage.
Check out the latest odds at the best online sportsbooks. Plus, it’s not too late to add more futures to your portfolio so take some time to check out our Power Four Conference Previews below.

Write Up Transparency

Be sure to follow me on X/Twitter @ColbyMBets to get my full card every day! Picks are always FREE.

Week 14 Results: 7-1 (+5.66u)

2025 Season Record: 58-53-2 (+11.80u)

2025 Heisman Trophy Odds

Julian Sayin has 27 touchdowns and just four interceptions for Ohio State this year - Ohio State Michigan Picks

Does Julian Sayin have a chance at winning the Heisman?

Odds are courtesy of BetOnline, one of our favorite online sportsbooks. Sign up today with Promo Code FREE250 for a 50% deposit bonus up to $250 as well as 100 Free Spins at the online casino.

  • Fernando Mendoza +135

  • Julian Sayin +135

  • Diego Pavia +275

  • Jeremiyah Love +2500

Heisman Trophy Insights

As championship week kicks off, the Heisman market has narrowed to a razor thin group of contenders. Indiana quarterback Fernando Mendoza and Ohio State quarterback Julian Sayin sit at the top. Two quarterbacks meeting in the Big Ten Championship. Two players tied for first in the Heisman odds. Two athletes with one final shot to make a statement before the College Football Playoffs.

As for the other two names above, Vanderbilt quarterback Diego Pavia delivered an outstanding season for the Commodores, but missing the SEC Championship removes any chance to strengthen his resume, which likely ends his run. Notre Dame running back Jeremiyah Love suffered a rib injury against Stanford this past weekend, holding him back from making another strong push at the finish line.

With those two not playing in a conference championship this weekend, I believe it nearly ends their chances to win this award, so I am essentially out on both of them.

Where is the value?

Although I am currently holding Pavia and Love Heisman tickets, I am not looking to hedge. I will let them ride. With Sayin and Mendoza going head to head this weekend, there is a clear way to approach both the award and the matchup. Ohio State is a 5.5 point favorite at the time of this write up. If you trust Ohio State to overwhelm Indiana and believe Sayin will drive the offense, take him to win it. If Mendoza struggles against the Buckeyes defense, it only boosts Sayin’s stock.

If you believe Mendoza is going to torch one of the best defenses in the country, you are getting a better number by backing Indiana to win. The Hoosiers moneyline is up to +188 on some books. With Mendoza listed at +135 to win the award, taking Indiana to win the Big Ten Championship may offer more value.

It all comes down to whether you are already invested in the Heisman market or stepping in at the last moment. If you are entering late and want action tied to the Big Ten Championship, the approach laid out above gives you the clearest and most logical path to attack this race. Either way, this matchup will define everything and deliver the final word on this race. This is going to be incredible.

Interested in More Content?

Get FREE Picks and Props Weekly

Sign up for
THE WEEKENDER NEWSLETTER

Follow me on X @ColbyMBets for all my picks and sports opinions. Follow Betting News on ‘X’ and Twitch and catch us on stream! Betting News is also on TikTok! Follow us for more picks and news every day!

In need of a sportsbook? Check out one of our favorites among our best online sportsbooks and sign-up for a bonus!