NASCAR Cup Series Brickyard 400 Predictions & Picks: Three Best Bets for Indy

2025 Brickyard 400 polesitter Chase Briscoe - NASCAR Cup Series 2025 Brickyard 400 Predictions, Picks & Odds

Today, the NASCAR Cup Series will take on one of the most famous tracks in motorsports in the Brickyard 400 at Indianapolis Motor Speedway (2:00 p.m. ET, TNT).

Last week, William Byron lost his grip on the points lead after his latest brush with bad luck. Will his resurgence start this week? Read on for Brickyard 400 predictions and picks and see which top U.S. sportsbooks you should use for today’s best NASCAR bets.

Bet on Brickyard 400 Odds at BetOnline and Bovada

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If you like to bet on NASCAR odds each week, look no further than BetOnline and Bovada.

Both of these sites offer odds on NASCAR Cup Series, Xfinity Series, and Craftsman Truck Series races, and you can also find series championship odds at both sites.

Why do we recommend both books instead of just one? Line shopping is a valuable part of successful sports betting, and one book may have a better number for one driver, while the other book may have a better number for another driver, so both can be useful on race day.

Additionally, line movement may occur at different times at different books. Therefore, you may get a more favorable line at one book over the other depending on the timing. Use these books in a cooperative manner to maximize your value and chances of success with NASCAR betting.

If you would like to learn more about these sports betting sites and the sportsbook bonuses you can get at them to bet on the Brickyard 400 and other NASCAR races, we have in-depth sportsbook reviews for each of them and several other top online sportsbooks.

Odds to Win the 2025 NASCAR Cup Series Brickyard 400

Odds are courtesy of Bovada.

  • Kyle Larson +400
  • William Byron +700
  • Chase Briscoe +800
  • Denny Hamlin +850
  • Ryan Blaney +1100
  • Tyler Reddick +1100
  • Christopher Bell +1200
  • Bubba Wallace +1600
  • Chase Elliott +1600
  • Chris Buescher +1600
  • Ty Gibbs +1600
  • Brad Keselowski +1800
  • Joey Logano +2500
  • Carson Hocevar +3000
  • Austin Cindric +3300
  • Kyle Busch +3300
  • Erik Jones +3500
  • Alex Bowman +4000
  • John Hunter Nemechek +6600
  • Josh Berry +6600
  • Michael McDowell +6600
  • Ross Chastain +8000
  • Ryan Preece +8000
  • A.J. Allmendinger +10000

Brickyard 400 Predictions and Picks

William Byron to finish in the top three (+175 at Bovada)

Several weeks ago, Byron was well on his way to the NASCAR Cup Series regular season championship. But after accruing a win, seven top fives, and nine top tens in the first 14 races, Bad Luck Billy has had a horrific run through June and July.

Starting with running out of gas while racing for the win at Michigan, Byron has finished 27th or worse five times in the last seven races and has found himself caught in the crossfire multiple times, including last week at Dover.

As a result, he now sits 16 points behind Elliott in the points, and if nothing else, a good result in the Brickyard 400 would be a welcome respite from his recent rotten run.

Byron will start sixth, the 14th time this season that he will start in the top 10. He’s converted seven of those 13 starts into top-10 finishes, including a win, three top 3s, and five top 5s.

Byron has finished in the top ten only once in four previous Brickyard 400 starts, but the man needs a little luck in his lane right now, and some faith here can’t possibly hurt.

Chris Buescher to finish in the top 10 (-125 at Bovada)

Buescher has five top 10s in his last seven races, including a ninth-place finish at Dover. This has helped him stay on the right side of the cutline for the playoffs, and he enters the Brickyard 400 with a 28-point advantage over Bubba Wallace, who occupies the last playoff spot, and a 44-point lead over Ryan Preece, who is the first man on the outside looking in.

That Buescher continues to get odds like this despite having an average finish of 13.8 and there being only three drivers (Larson – 13, Elliott – 12, and Bell – 12) with more top 10s this season is a bit surprising. But it also makes him an easy pick here, especially after he qualified seventh.

Chase Briscoe to finish in the top five (+175 at Bovada)

After finishing second at Sonoma and Dover, Briscoe will start on pole in the Brickyard 400, his fifth pole of the season.

Through 21 races this season, the polesitter has finished in the top ten 14 times, with a dozen of those finishing being top fives. Two belong to Briscoe, who finished fourth in the Daytona 500 and third in the Coca-Cola 600 after starting on pole.

You have to like his percentages to add to that in this spot, especially when he is tied for third in the Cup Series with eight top-five finishes this season.

Other NASCAR Betting Content

Did you enjoy this Brickyard 400 breakdown? Throughout the season, you can find predictions, picks, and expert NASCAR betting insight for many Cup Series, Xfinity Series, and Truck Series races, as well as updates on the latest championship odds.

Are you new to betting on NASCAR races and odds? Check out our NASCAR betting guide to get your knowledge up to speed before you bet on the upcoming action.

In addition to our dedicated betting guide, several of our sports betting guides are useful for wagering on NASCAR odds. That includes our guide to golf finishing position bets, which are similar in scope and approach to NASCAR finishing position bets.